Caffeine- The bitter, white crystalline xanthine alkaloid caffeine is found in tea, coffee, soft drinks, chocolates, pain relievers, and a variety of over the counter medications. It is a psychoactive stimulant drug that causes increased alertness by stimulating the central nervous system. For the same reason, many people feel more energetic after consuming it. It even elevates the mood but these effects do not last for long. The effects of caffeine usually last for about five to six hours, though caffeine sensitivity varies from person to person. It has been found that people who consume lot of caffeine on a daily basis soon develop less sensitivity and may need to increase their intake to enjoy the same effect. Being a diuretic, a person consuming caffeine may have to urinate more often.

Cinnulin is extracted from cinnamomum burmannii and is helpful for type II diabetes and weight loss. Studies show that cinnulin increases lean body mass and helps in reduction in body fat. It is used by people who are obese or who want to loose weight. Cinnulin can also be extracted from cinnamomum zeylanicum and cinnamomi cassia. Cinnulin, a water extract of cinnamon has become popular as it promotes healthy blood glucose levels. It ensures healthy glucose metabolism by utilizing the insulin in body more effectively. According to USDA studies cinnamon promotes healthy cholesterol levels in type II diabetes. Cinnulin is widely used by diabetic and obese patients.

Citrulline Malate is a combination of citrulline and malate. It is showing strong evidence of improving muscle weakness. This is beneficial for those involved in bodybuilding as a muscle strengthener.

Creatine Malate is made from malic acid and creatine monohydrate. This substance has a compound made using three creatine molecules with one molecule of malic acid. Creatine malate is odorless and white in color. Creatine malate is derived from arginine, glycine and methionine and is helpful in producing as well as in circulating ATP, responsible for muscular contraction. The regular supplementation of creatine shows an increase in the total body weight, muscle strength, brain function, cardiovascular ability and overall performance in athletics. Creatine malate has malic acid which helps in providing energy and monohydrate increases the explosive strength and muscle torque. It also maintains free levels of testosterone and prevents catabolism. Creatine malate is efficient in transporting creatine to the muscle cells and yields good strength such that there is no cramping, stomach upset or water retention. Body builders and athletes can certainly benefit due to malate supplementation. Similarly, men and women as well can derive benefit using this supplementation.

Di-Sodium Phosphate is an essential mineral and a life-supporting element for the human body. It is derived from plants, water and animals. An imbalance of di-sodium phosphate can lead to chronic diseases and serious consequences. Many a times it is added to food to improve taste, as a preservative, to improve texture and to prevent the growth of molds. Most of the prepared and processed food contains di-sodium phosphate. It regulates body fluids, blood pressure, enhances heart activity and provides various nutrients to the cells. A proper balance of this mineral must be maintained by our body. It is the kidney and the intestines which adjust sodium concentration in our body. The level of sodium decreases due to secretion and perspiration and increases while eating fast food like burgers and pizzas at restaurants.

Glycine is known to have the ability to stimulate specific brain receptors as well as beneficial for building proteins in the body. It is used as a supplement for many ailments such as strokes or memory loss.

L-Arginine AKG is a salt of amino acid arginine and alpha-ketoglutaric acid, and is widely used as a body building supplement. Its components assist in the metabolism of nitric oxides. Arginine and alpha-ketoglutarate are forerunners of polyamines and nitric oxide, which take part in a number of metabolic functions. Its supplements enhance growth hormone and insulin secretion with anabolic effects in postoperative patients. Their intermediary metabolites, glutamine and proline, can also help promote recovery from trauma. In animal studies, it increased the levels of glutamine and arginine in skeletal muscles and stimulated the immune system function as compared to animals which did not receive it. It can also improve host-defense mechanisms, especially during injury and acute stress.

L-Citrulline AKG- L-Citrulline Alpha Ketoglutarate is a nutritional supplement ingredient, mainly because of the citrulline contained. Citrulline is actually an amino acid that is synthesized by the body into the much more needed conditionally essential amino acid called arginine, which is deemed a precursor to nitric oxide. It seems like the synthesizing of nitric oxide is somehow enhanced by the addition of alpha ketoglutarate, the chemical bonding of AKG with arginine is apparently providing this effect. The overall nitric oxide levels in the blood are elevated by supplementation of L-Citrulline AKG, which in turn apparently stimulates opening of blood vessels, more accurately vasodilation. Citrulline, as an alpha amino acid, is deemed a vital intermediate in the ornithine cycle, a vital biochemical reaction that produces urea out of ammonia in the liver.

L-Histidine AKG- L-Histidine Alpha Ketoglutarate is a precursor to histamine, a neurotransmitter. Histidine is one of the standard amino acids, twenty in count, that are naturally present in proteins. Humans are able to synthesize it, but in infants it is necessary to supplement this amino acid. L-Histidine Alpha Ketoglutarate is a supplemental formula for histidine, which is then synthesized by the body into histamine. Histamine is generally stored or inactivated. Four histamine receptors have been identified, with various functions, depending on the location. The H1 histamine receptor is, among other functions, responsible for causing vasodilation, bronchial smooth muscle contraction, immunologic reaction to pain and itching caused by insect stings, motion sickness and other. H2 histamine receptor stimulates gastric acid release. H3 histamine receptor controls the neurotransmitter release in central and to a lesser part peripheral nervous system. H4 is involved in chemotaxis.

L-Tyrosine is a proteinogenic polar amino acid, deemed not essential because it can be synthesized by the human body. As a member of the amino acid group that is being used by cells to build proteins, this building block derived its name from the Greek word tyros, which means cheese, because it was discovered in the cheese protein casein. L-Tyrosine can be synthesized from phenylalanine and can be found in foods high on protein, like soy products, poultry, cheese, bananas, dairy products and several seeds, including the sesame seeds. The unique phenol functionality and the occurrence in proteins that belong to the signal transduction process, make this amino acid different. Tyrosine can be converted by tyrosine hydroxylase enzyme into levodopa, a psychoactive drug that is used, among other uses, for clinical treatment of Parkinson’s disease. It is also involved in the synthesis of dopamine, norepinephrine and epinephrine.

Magnesium Phosphate is naturally found occurring inside the cells of muscles and nerves. Magnesium helps in the proper absorption of phosphorus. It helps regulating and maintaining the nerves. It acts as a nerve stabilizer. It has the ability to promote muscle and nerve relaxation. It prevents spasmodic pains, cramps and muscle strains. It also helps in preventing menstrual cramps. It fights against chronic fatigue. It also aids in the gastrointestinal system. It prevents flatulent colic, pains in the abdomen, and excessive gas. It also helps in regulating the blood pressure, which is good for treating and maintaining cardiovascular problems. It also helps in taking care of the eyesight.

NAD- Nicotinamide Adenine Dinucleotide is found in all living cells, and it is a dinucleotide and a coenzyme. NAD can be synthesized by the human body, it can be derived either from tryptophan or from aspartic acid. It can also be recycled by salvaging preformed nicotinamide into NAD. Nicotinamide Adenine Dinucleotide has multiple vital activities to perform in human metabolism. As a coenzyme, it is involved in redox reactions, but also as a provider of adenosine diphosphate – ribose clusters for ADP-ribosylations, as a precursor for the molecule cyclic ADP-ribose, as a substrate for DNA ligases of bacteria, plus removal from acetyl groups out of proteins by sirtuins that employ NAD for that purpose. Nicotinamide Adenine Dinucleotide is available as a dietary supplement in the reduced NADH form.

Potassium Phosphate is the coined or generic name for phosphate ions and potassium’s salt which is classified into three different substance; Monopotassium phosphate, Dipotassium phosphate and tripotassium phosphate. Monopotassium phosphate is commonly used in fertilizers, fungicides and several food additives. Among the other types of Potassium Phosphate, Monopotassium phosphate is considered as the soluble salt. On the other hand, Dipotassium phosphate is also used in fertilizers, food additives and as a buffering agent but compared to Monopotassium; it is also a soluble salt but is high in water content like tripotassium phosphate. Generally, all types of Potassium Phosphate are frequently used as fertilizers and food additives and though they might differ in some area, almost all of them bear the same quality with one another.

Taurine is an amino acid found within muscle tissue. It is the second most abundant amino acid found in the body.

Trimethylglycine, which is also known as betaine, due to the source it was discovered in, Beta vulgaris or sugar beets, is an organic compound that is deemed related to trimethylaminoethanol, or choline. To diversify it from other betaines, trimethylglycine is often called glycine betaine as well. Humans generally ingest betaine through their diet, because it is high in content in wheat, whole wheat, shellfish, sugar beets and spinach. It can also be formed in the human body out of choline. As a potential methyl donor, trimethylglycine, or TMG for short, is in the same provider group with Vitamin B12, the folic acid, choline and S-adenosyl methionine, or SAMe. TMG also plays a vital function in the production of carnitine, furthermore it works in protecting kidneys and the liver.