Caffeine is the most widely available legal psychoactive stimulant drug. Also known as theine, methyltheobromine and trimethylxanthine, this xanthine alkaloid is not only found in coffee beans, but also in guaranine that is derived from guarana, mateine derived from mate, theine which is found in various teas and the kola nut, which is the base flavor of various Cola soft drinks. It stimulates the central nervous system, where it restores alertness and wards off drowsiness. Caffeine is also know to display certain diuretic properties, is an ergogenic, an atagonist of the adenosine receptors, and a cAMP levels increasing factor. It seems that caffeine helps prevent the onset of Parkinson’s disease and in the long run lowers the possibility of developing a heart disease.

Green Tea Extract is of immense use to treat body ache, headaches and poor digestion. The green tea extract contains polyphenols to high levels and is an opulent source of antioxidant. It has the power of fighting free radicals more than vitamin E. the polyphenols present in green tea extract protect against respiratory and digestive infections. It blocks the carcinogens actions that promotes cancer and reduces the cholesterol levels. Green tea extract helps in metabolizing fat. The dieters can feel the weight loss without side effects and jitters. The green tea extract decreases the heart disease risk and also helps in preventing liver failure. The benefits of green tea extract are many, but as it contains caffeine, medical experts should be consulted prior to using it. Green tea extract also defends dental plaque. Green tea extracts prevents even liver transplant failure, but pregnant women should take green tea only after doctor consultation.

Guarana is a climbing plant of the Sapindaceae family native to the Amazon basin. Guarana is best known for its fruit and seeds. Guarana extracts contain naturally high amounts of caffeine which the plant uses in defense against pathogens. Its extracts are a natural and abundant source of caffeine in most parts of the world. It is added to soft drinks, herbal tea, energy shots and used in capsules. The extracts have a positive effect on cognition and they also increase memory retention and physical endurance. A 2007 study on human pilots showed its positive effects on memory, alertness and mood. It is also reported to have antioxidant and antibacterial effects.

Kola Nut, bitter brown seed that contains caffeine. Once used to make cola soft drinks, Kola Nut has been replaced by artificial flavourings in most beverages.

Methylxanthines (Caffeine) is basically a type of bronchodilator, methylxanthine is considered highly effective in the treatment of COPD. Due to its ability to relax the airways, it enables the patient to breathe more easily. For the same reason, it is believed to improve respiratory muscle strength when administered orally or intravenously. Caffeine, a widely used psychoactive substance, belongs to this group of compounds called as methylxanthines. Caffeine gives rise to number of neurological side effects such as anxiety, insomnia, restlessness, and tachycardia. On the other hand, low to moderate consumption of caffeine can lead to positive effects such as enhanced alertness, energy and better concentration. Some people may experience withdrawal symptoms after about 12 to 24 hours after sudden cessation of caffeine consumption while some individuals may report of such symptoms within 3 to 6 hours.

Theobromine- The bitter alkaloid found in chocolate is known as theobromine. It comes from the cacoa plant and is found in chocolate as well as chocolate free foods that are consist of theobromine. Theobromine belongs to the methylxanthine class of chemical compounds. It is found in the leaves of the tea plant, the kola or cola nut and acai berries. No bromine is present in theobromine, despite the name. The properties of theobromine are that it is souluble in water, is crystalline, is a bitter powder, is listed as white or colorless in color. It is considered a lesser homologue because it has a lesser effect to caffeine. Theobromine is the kind of isomer which belongs to paraxanthine and theophylline at the same time. It is basically a xanthine having two methyl groups.

Theophylline is a drug which belongs to the xanthine family. These substances are aromatic in nature and consist of a purine ring which is substituted with different chemical groups at different carbon positions to form different compounds chemically. In case of theophylline the purine ring has one methyl group substituted at carbon number 1 and 3 and one oxygen atom substituted at carbon number 6 and 2. Theophylline was originally extracted from tea leaves and was initially used to increase the rate of urination (diuresis); later it found more uses as a drug because of its effects on the respiratory and circulatory systems. However, it has many side effects; therefore, presently it is prescribed quite judiciously.