Bioperine- Basically a pure and safe nutritional supplement of piperine, Bioperine can have several positive effects on our body. It contains about ninety five percent of piperine that is known to enhance the bioavailability of nutrients. As a result, bioperine intake helps in rapid absorption of nutrients from the gastrointestinal tract. Owing to its affinity for the fatty tissue, it even interacts with the lipid component of the intestinal cell membrane thereby allowing further nutrient permeability. It is quite popular due to its ability to enhance thermogenesis. This is how it works - the piperine present in bioperine stimulates the release of catecbolamines that trigger thermogenesis in the GI tract thus, making more energy available for digestion. It can be combined with other nutrients too to improve the health of human beings as well as animals.

L-Arginine is one of the most common naturally occurring amino acids. In adults, arginine is deemed semi-essential, while for infants it is believed to be essential alpha amino acid. The functions of L-Arginine are multiple, it plays roles in the healing of wounds, immune function, hormone release, ammonia removal and cell division. It is also believed to be a precursor of nitric oxide, increasing the muscle mass, reduce body fat, decrease blood pressure and a dozen other functions, such as reducing the recuperation time after a serious injury, bone fractures and similar in particular. Since that L-Arginine can be produced by the human body, ingestion is conditionally not necessary, but sources include dairy products, meat such as beef and pork, poultry, but also vegetables like nuts, seeds, oatmeal, wheat flour and more.

L-Ornithine is produced when the enzyme arginase reacts on L-arginine, whereby urea is being created. Consequentially, ornithine seems to be a vital part of the urea cycle, the disposal of ammonia and the removal of excess nitrogen. Although ornithine is not coded for by the DNA, which means that it is not a part of the protein synthesis processes. Despite this fact, the urea cycle plays a big part in arginine biosynthesis, which means that as an intermediate in a metabolic process, ornithine still retains vital importance. L-Ornithine is gaining on popularity as a nutritional supplement, in particular with the body building circles, where it is propagated as a muscle building and fat loss agent. It is furthermore stated that L-Ornithine may be initiating the release of growth hormones in the body.

Magnolia Bark usage has been adopted from traditional Chinese medicine, where it was being used as an anti depressant. In conjunction with other ingredients, like Pinellia ternata, Poria cocos and Zingiber officinale, it has displayed effects that rival the ones of Prozac. Houpu, which is how Chinese call magnolia officinalis bark, contains polyphenolic compounds, mangolol, which is a bioactive compound with antifungal properties; and honokiol, a biphenolic compound which is known as an anxiolytic, anti-emetic, anti-depressant, antithrombotic and anti-bacterial. Honokiol in particular is a very potent anti-tumorigenic and neurotrophic compound, used to combat melanoma, leukemia, myeloma and sarcoma, as well as a multitude of cancers. It is also a known promoter of neurite outgrowth and has neuroprotective effects. There are no adverse effects known.

Melatonin refers to a hormone made by a brain part called the pineal. Melatonin helps bodies in understanding the time to go to bed and sleep and also the time to wake up. Melatonin is also available in pill form as they are available in natural and synthetic forms. Natural melatonin is manufactured from the pineal glands of the animals and this can get contaminated with virus. This is the reason that it is not recommended. Synthetic melatonin has no risk involved. Melatonin is used in treating insomnia and prevents jet lag. Melatonin promotes health or treats disease has very little scientific evidence. Some people have reported headache, stomach discomfort and depression, however further study is being done. Melatonin is available without the prescription of a doctor in the drug stores and health food stores in the United States. But, as it is not regulated by the government, the safety, purity and effectiveness is far from being guaranteed.

N-Acetyl-5-Methoxytryptamine is more commonly known as the hormone melatonin, a naturally produced chemical messenger made by the pinealocytes, the cells in the pineal gland, which is located in the brain. Melatonin is involved in the circadian cycle, where it is believed that it chemically lowers the body temperature and causes drowsiness. The pineal gland produces melatonin only when it is dark, i.e. during the night. It is furthermore believed that melatonin interacts with leptin, whereby the leptin levels are lowered. Actually it was found that the interaction with insulin stimulated the leptin levels, which seems to be responsible for appetite suppression during sleep. Further investigation provided evidence that melatonin displays strong antioxidant properties. N-Acetyl-5-Methoxytryptamine, or melatonin, has been studied extensively for treatment of many diseases, including treatment of drug abuse, cancer, seasonal affective disorder and depression.

Piper Nigrum(Black Pepper) or black pepper, which is a common spice, has medicinal properties. It is a tropical plant and India is the largest producer of Piper Nigrum. It possesses anti-bacterial and anti-inflammatory properties. It acts as an antioxidant agent also. Black Pepper contains essential oil, which acts against intestinal flatulence and also stimulates sweating and urination. The essential oil found in Piper Nigrum stimulates stomach cells to produce HCl acid, which helps in digestion. Piper Nigrum also helps in absorption of certain essential micronutrients like coenzyme Q-10, beta-carotene and EGCG. Pepper has its contribution in Ayurvedic medicines also. Pepper seeds are used to prepare sinusitis relieving medicines. It also used for sore throat and dry cough.

Ziziphus Jujuba is also known as the Indian Jujube. These fruits are applied on cuts and used for pulmonary ailments and fevers. The dried ripe fruit is also used as a mild laxative. They are a rich source of protein, calcium, thiamine, citric acid, iron and phosphorus. The dried leaves of the plant are used in poultices for liver trouble, asthma and fever. The juice of the root bark is used to alleviate gout and rheumatism. The flowers are even used to make a lotion for the eyes.