Chromium Polynicotinate is a more biologically active component than other forms of Chromium. CP helps to control blood sugar levels and can be dangerous to the blend of fats, cholesterol, and proteins. It is helpful in the metabolism of glucose and is important for getting energy. Chromium polynicotinate is a mineral that adds a hormone-like regulation to develop carbohydrate metabolism. As all carbohydrates finally are reduced to simple glucose in the body. Chromium polynicotinate provides the mediator action by plugging serum glucose through the bloodstream to the muscle cell directly. Chromium is essential for glucose regulation, carbohydrate metabolism, and energy production. It may also produce anabolic effects, but with no side effects.

Guarana, a stimulant derived from the seeds of the Brazilian Guarana plant. Guarana is used to increase alertness and help fight fatigue. It contains caffeine and is usually associated with an "energy crash" several hours after taking a large dose.

Gymnema Sylvestre is native to India, predominantly in tropical forests of India. This herb has traditionally been used in the Indian eclectic alternative medical system as the naturopathic treatment for diabetes. The active ingredients or bioactive constituents are a group of gymnemic acids, which have antidiabetic and anti-inflammatory as well as antisweetener properties. If used for a while, gymnema sylvestre, or rather the gymnemic acids, have the effect of reducing the blood sugar level. These glycosides are found in an extract of the leaves and it seems that the acids have a similar structure to saccharose. Besides the gymnemic acids, the plant contains also saponins, quercitol, stigmasterol and also some amino acid derivatives, namely trimethylamine, betaine and choline. When the leaves of gymnema sylvestre are chewed, you temporarily lose the ability to taste sugar.

Hoodia Gordonii grows in Namibia and South Africa naturally. It is a leafless spiny plant useful for medicinal purposes. These flowers are pollinated by flies mainly as they smell identical to rotten meat. Hoodia is known long by indigenous population and is infrequently used for treating small infections and indigestion. This is used to suppress appetite during long hunting trips such as Kalahari Desert that interests more tourists. Hoodia Gordonii was prominent for it appetite suppressing effect and hence was collaborated with Pfizer, a pharmaceutical company to deal with obesity. However, it was stopped as it is stated to have indications of effects on liver. Hoodia Gordonii is wild harvested by individuals as well as by few companies that are granted license. However, there is no evidence of Hoodia working in humans as appetite suppressant. Due to the lack of clarity and fear of breaking down of liver, it is not recommended for obesity.